IIT-Madras and IRFC Establish India’s First Single Cell Omics Translational Research Lab
On November 18, 2025, the Indian Institute of Technology (IIT) Madras, in collaboration with the Indian Railways Finance Corporation (IRFC), inaugurated India’s first Single Cell Omics Translational (SCOT) research laboratory. This pioneering facility aims to enhance the capabilities of medical research in the country, focusing on early diagnosis, disease prognosis, biomarker discovery, and drug screening across various diseases.
Significance of the SCOT Lab
The SCOT lab is equipped with state-of-the-art instrumentation that will facilitate advanced research in single-cell biology. This innovative approach is crucial for understanding complex diseases and developing targeted therapies. The lab’s research scope includes:
- Cancer
- Cardiovascular diseases
- Infectious diseases
- Inflammatory conditions
- Metabolic disorders
- Other non-communicable diseases
Funding and Support
The establishment of the SCOT lab is made possible through a Corporate Social Responsibility (CSR) grant of Rs 10.83 crore provided by IRFC. This funding underscores the commitment of both institutions to advance healthcare research and innovation in India.
Goals and Objectives
The primary objectives of the SCOT lab include:
- Accelerating research in single-cell biology.
- Enhancing drug discovery processes.
- Identifying biomarkers for various diseases.
- Innovating in translational healthcare.
According to V Kamakoti, Director of IIT Madras, this collaboration marks a significant milestone in India’s journey towards drug discovery and precision medicine. He emphasized the lab’s potential to develop solutions that improve early diagnostics and targeted therapeutics.
Impact on Medical Research
Usha Venugopal, Member (Finance) of the Ministry of Railways, expressed optimism about the SCOT lab’s contributions to medical research. She stated that the facility would strengthen India’s capabilities in early diagnosis and therapy development. The collaboration between IIT Madras and IRFC exemplifies how institutions can work together to achieve larger national goals, ultimately aiming for better health outcomes.
Training and Development
Anubama Rajan from the Department of Medical Sciences and Technology at IIT Madras highlighted the lab’s role as a national training hub. It aims to bring together clinicians, scientists, and engineers to foster the next generation of India’s translational research ecosystem. This initiative is expected to:
- Enhance drug discovery efforts.
- Facilitate early diagnostics.
- Promote precision healthcare.
By training future clinicians and scientists, the SCOT lab aims to build a robust foundation for ongoing medical research and innovation in India.
Future Prospects
The establishment of the SCOT lab is a crucial step towards enhancing India’s research capabilities in healthcare. As the facility begins its operations, it is anticipated to yield high-impact outcomes that will contribute to the nation’s health landscape. With a focus on single-cell analysis, the lab is poised to make significant strides in understanding diseases at a molecular level, ultimately improving patient care and treatment options.
Conclusion
The collaboration between IIT Madras and IRFC to establish the SCOT lab represents a significant advancement in India’s medical research capabilities. By focusing on single-cell omics, the lab is set to play a pivotal role in early diagnosis, targeted therapies, and the overall enhancement of healthcare innovation in the country.
Note: The information presented in this article is based on the latest developments as of November 2025.

